Synthesis, Structure and Biological Activities of 2-(4-Methoxybenzoyl)-N-phenyl-2-(1,2,4-triazol-1-yl)thioacetamide

The title compound, 2-(methoxybenzoyl)-N-phenyl-2-(1,2,4-triazol-1-yl)thioacetamide was synthesized by several reactions from 4-methoxyacetophenone, triazole and phenyl isothiocyanate. The structure was identified by elemental analysis, 1H NMR, MS and IR. The single crystal structure of 2-(methoxybenzoyl)-N-phenyl-2-(1,2,4-triazol-1-yl)thioacetamide was determined with X-ray diffraction. The preliminary bioassays show that the title compound exhibits weak antifungal activities and plant-growth regulatory activity.

作 者： LIU Fa-qian QIN Yong-qi LI Wei-hua YANG Shuang-hua LU Lu-de YANG Xu-jie WANG Xin HOU Bao-rong   作者單位： LIU Fa-qian,LU Lu-de,YANG Xu-jie,WANG Xin(Materials Chemistry Laboratory, Nanjing University of Science and Technology, Nanjing 210094, P. R. China)

QIN Yong-qi,YANG Shuang-hua(College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P. R. China)

LI Wei-hua(College of Chemistry and Chemical Engineering, Ocean University of China, Qingdao 266033, P. R. China;Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, P. R. China)

HOU Bao-rong(Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, P. R. China) 

刊 名： 高等學(xué)校化學(xué)研究（英文版）  ISTIC SCI 英文刊名： CHEMICAL RESEARCH IN CHINESE UNIVERSITIES  年，卷(期)： 2005 21(3)  分類號： O6  關(guān)鍵詞： 1,2,4-Trizole,Thioamide,Crystal structure,Biological activities  

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