重囗另类BBWSeⅹHD,av狼论坛,精品一卡2卡三卡4卡乱码理论,体育生gv老师浪小辉3p警察

In-depth cDNA Library Sequencing Pro

時(shí)間:2023-05-02 21:53:30 生物醫(yī)學(xué)論文 我要投稿
  • 相關(guān)推薦

In-depth cDNA Library Sequencing Provides Quantitative Gene Expression Profiling in Cancer Biomarker Discovery

procedures may allow detection of many expres-sion features for less abundant gene variants. With the reduction of sequencing cost and the emerging of new generation sequencing technology, in-depth sequencing of cDNA pools or libraries may represent a better and powerful tool in gene expression profiling and cancer biomarker detection. We also propose using sequence-specific subtraction to remove hundreds of the most abundant housekeeping genes to in-crease sequencing depth without affecting relative expression ratio of other genes, as transcripts from as few as 300 most abundantly expressed genes constitute about 20% of the total transcriptome. In-depth sequencing also represents a unique ad-vantage of detecting unknown forms of transcripts, such as alternative splicing variants, fusion genes, and regulatory RNAs, as well as detecting mutations and polymorphisms that may play important roles in disease pathogenesis.

作 者:   作者單位:   刊 名: 基因組蛋白質(zhì)組與生物信息學(xué)報(bào)(英文版)  英文刊名: GENOMICS、PROTEOMICS & BIOINFORMATICS  年,卷(期): 2009 ""(1)  分類號(hào): Q5  關(guān)鍵詞: cDNA sequencing   sequencing depth   expressed sequence tag   sequence-specific subtraction   biomarker   mutation detection  

【In-depth cDNA Library Sequencing Pro】相關(guān)文章:

Cloning and Sequencing of a Full-Length cDNA Encoding the RuBPCase Small Subunit (RbcS)in Tea (Camellia sinensis)04-29

甜菜夜蛾cDNA文庫(kù)的構(gòu)建04-30

Treatment of sauce wastewater by sequencing biological-chemical reactor (SBCR)04-27

英文求職信-Library Sciences - Librarian04-26

大鼠肌肉素cDNA克隆及表達(dá)04-29

如何利用圖書館How to Use the Library05-19

Our School Library英語作文(通用10篇)04-11

Simultaneous Nitrogen and Phosphorus Removal by Denitrifying Dephosphatation in a (AO)2 Sequencing Batch Reactor04-29

人溶菌酶基因cDNA的克隆和序列分析04-26

大豆干旱和低溫cDNA文庫(kù)的構(gòu)建與檢測(cè)04-30

主站蜘蛛池模板: 东乌| 离岛区| 体育| 博客| 舒兰市| 衡东县| 岚皋县| 孙吴县| 越西县| 托克托县| 团风县| 灵武市| 茂名市| 巨鹿县| 西乌珠穆沁旗| 镇赉县| 长沙市| 水富县| 清苑县| 栾城县| 遂川县| 芒康县| 手游| 苍山县| 宜良县| 城市| 井陉县| 金平| 新乐市| 乌拉特后旗| 太湖县| 罗江县| 江安县| 红安县| 淮阳县| 项城市| 南通市| 壶关县| 松江区| 东乌珠穆沁旗| 玉屏|